Endocrine Abstracts

In 2010 non-communicable diseases were shown to be the most important cause of mortality worldwide on the WHO global status report, with diabetes the 4th most common disease causing death. Type 1 diabetes Mellitus (T1DM) is the most common form of diabetes in children and young people. There is a paucity of data regarding T1DM in children in West Africa, in particular in The Gambia.Aim: To explore the clinical presentation and outcome of children with T1...

Self-monitoring of blood glucose (SMBG) is an important part of diabetes management. Continuous glucose monitoring (CGM) provides real-time measurement of users’ glucose levels. The advantage of CGM is the availability of constant information about glucose levels which helps to predict hyper and hypoglycaemia and to adjust the insulin doses accordingly. NICE guidelines recommend that children and young people with type 1 diabetes and persistent problems with hypoglycaemia...

A 22-year-old woman with hypophosphataemic rickets was diagnosed at age four when she presented with short stature and valgus deformity of the lower limbs. Biochemical testing, genetic screening and radiological investigation of her family showed no abnormality and it was concluded that she had a de novo mutation.She was treated with 1α-calcidol and phosphate Sandoz with regularly monitored biochemistry. She had poor adherence to her medicati...